Interstitial Cystitis Advice

I think it worthwhile to ask Histo-Chemists in Entomology and Parasitology to analyze the research findings for IC. Enough is known about tissue damage, biomarkers and treatments to attempt a disease model for phantom Cyclorrhapha that will either work or won’t.

Cyclorrhapha are flies that have parasitic larvae. Minor flies in this sub-order live closely with pets and humans, but people are not familiar with them. They can live invisibly in the environment.

Consider the following:

IC is found in humans and lower mammals. Cyclorrhapha jump species to infect both humans and lower mammals.

IC elevates urinary pH. Cyclorrhapha parasitism alkalinizes tissue between 8-9.

IC urine is sterile. Cyclorrhapha parasitism is anti-microbial.

IC thins bladder epithelium 1-2 cell layers. Cyclorrhapha scrape and liquefy tissue before ingesting it.

IC has flare-ups, remissions and complete remissions with and without treatment.
Cyclorrhapha parasitism is self-limited and only occurs during early embryogenesis. The disease ends unless the patient is infected again.

IC patients have wide ranging symptoms. Cyclorrhapha parasites do not multiply in tissue, so symptoms would depend on the strength of the parasitic burden. A light infection would bring more tolerable symptoms than severe infection or repeated infections.

IC produces petechial hemorrhages/hunner’s ulcers in the upper bladder. Cyclorrhapha parasites can’t live indefinitely in urine, and would seek dryer embedding places to mature. They would naturally move above the urine line at the time.

IC patients have atopic allergies. I don’t know what these allergies are, but assume they are in the epithelium of the skin, eyes and sinuses. The proposed disease looks more like an allergy than parasitism. External genital sores are another sign the target is epithelium.

Most IC Patients Are Female. Female genito-urinary anatomy is more accessible than male. Menstruation and hormonal chemistry may play a role.

IC sometimes affects more than one family member, such as mother and daughter. The parasite probably is in the shared environment. It lives surreptitiously with humans.

94% of I.C. Patients have minute quantities of Antiproliferative factor in urine. APF is a small 0-linked glycopeptide. I have read a segment of the glycopeptide is also found in the chemistry of cyclorrhapha.

Thank you for reading my post.